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Department of Molecular Medicine
 

[ default picture ] Ibtissam  Echchgadda,  Ph.D.

Instructor

Profile and Contact Information | Research

RESEARCH

 

Research Program

 

Selected Publications

  1. Song CS, Echchgadda I, Baek BS, Ahn SC, Oh T, Roy AK, and Chatterjee B: (2001) DHEA-sulfotransferase gene induction by bile acid activated farnesoid X receptor. J Biol Chem. 276: 42549-56.
  2. Echchgadda I, Song CS, Roy AK, and Chatterjee B: (2004) DHEA-sulfotransferase is a target for transcriptional induction by the vitamin D receptor. Mol Pharmacol. 65: 720-9.
  3. Echchgadda I, Song CS, Oh TS, Cho SH, Rivera OJ, and Chatterjee B: (2004) Gene regulation for the senescence marker protein DHEA-sulfotransferase by the xenobiotic-activated nuclear pregnane X receptor (PXR). Mech Ageing Dev. 125: 733-45.
  4. Chatterjee B, Echchgadda I, and Song CS: (2005) Vitamin D receptor regulation of the steroid / bile acid sulfotransferase SULT2A1. Methods Enzymol. 400: 165-91.
  5. Song CS, Echchgadda I, Seo YK, Oh T, Kim S, Kim SA, Cho S, Shi L, and Chatterjee B: (2006) An essential role of the CAAT / enhancer binding protein-alpha in the vitamin D-induced expression of the human steroid / bile acid-sulfotransferase (SULT2A1). Mol Endocrinol. 20: 795-808.
  6. Seo YK, Chung YT, Kim SY, Echchgadda I, Song CS, and Chatterjee B: (2007) Xenobiotic- and Vitamin D-responsive induction of the steroid / bile acid-sulfotransferase Sult2A1 in young and old mice: the role of a gene enhancer in the liver chromatin. Gene 386: 218-23.
  7. Echchgadda I, Song CS, Oh T, Ahmed M, De La Cruz IJ, and Chatterjee B: (2007) The xenobiotic-sensing nuclear receptors PXR, CAR, and orphan nuclear receptor HNF 4alpha in the regulation of human steroid-/bile acid-sulfotransferase. Mol. Endocrinol. 21: 2099-111.
  8. Shi LH, Ko SY, Kim SY, Echchgadda I, Oh T, Song CS, and Chatterjee B: (2008) Loss of androgen receptor in aging and oxidative stress through Myb protooncoprotein-regulated reciprocal chromatin dynamics of p53 and poly(ADP-ribose) polymerase PARP-1. J Biol Chem. 283: 36474-85. Online as doi/10.1074/jbc.M805980200.
  9. Echchgadda I, Kota S, Dela Cruz I, Sabbah A, Chang T, Harnack R, Mgbemena V, Chatterjee B, and Bose S: (2009) Anticancer oncolytic activity of respiratory syncitial virus. Cancer Gene Therapy E-Pub ahead of print publication. doi/10.1038/cgt.2009.34.

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